[Python] Applying a function to two columns in a data frame

I want to create new columns in a data frame containing biking data (start station and end station names, and trip duration). I want to assign the different stations to a specific neighborhood. However, I am not managing to apply the function to both the start station and end station columns. I would appreciate any guidance. Below is my code:

#Assign stations to neighborhood

Shadyside = ['Ivy St & Walnut St', 'Shady Ave & Ellsworth Ave','S Negley Ave & Centre Ave','Penn Ave & S Whitfield St',
'Pierce St & Summerlea St']

#print(Shadyside)
def station(x):
for i in Shadyside:
#print(i)
if re.search(r'i', x) != None:
return 'Yes'
else:
return 'No'
Biking_data['Shadyside'] = Biking_data['Start Station'].apply(station)
print(Biking_data)


I tried the above code just on one column to see if the function works. But then stations not in Shadyside are said to be in the neighborhood.

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